TETRAMETHYLAMMONIUM GLYCINATE - A NEW REAGENT FOR IMPROVED PYRROLE SYNTHESIS BY [3+2] CYCLIZATION

被引：9

作者：

ANSARI, MA ^{[1
]}

CRAIG, JC ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

来源：

SYNTHETIC COMMUNICATIONS | 1991年 / 21卷 / 18-19期

关键词：

D O I：

10.1080/00397919108021790

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The novel reagent tetramethylammonium glycinate has been introduced as the most effective glycine derivative for the convenient synthesis of 4,5,6,7-tetrahydroisoindoles (or pyrroles unsubstituted in the 2 and 5 positions) from 1,3-dicarbonyl compounds by [3+2] cyclization. The reaction has been shown to be catalyzed by 2,6-di(tert.butyl)pyridine reagents to triple the reported yield.

引用

页码：1971 / 1979

页数：9

共 12 条

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