HEMORRHAGIC MYONECROTIC THROMBOTIC AND PROTEOLYTIC ACTIVITIES OF VIPER VENOMS

被引：37

作者：

TU, AT

HOMMA, M

HONG, BS

机构：

[1] Department of Biochemistry, Colorado State University, Fort Collins, CO

来源：

TOXICON | 1969年 / 6卷 / 03期

关键词：

D O I：

10.1016/0041-0101(69)90117-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Histolysis, thrombosis and proteolysis produced by venoms of vipers (Viperidae) from Asia, Europe and Africa were investigated. Some venoms showed hemorrhagic effects but not myonecrotic activity. Only Russell's viper from Thailand caused thrombosis. Four substrates were used to test for proteolytic activity of snake venoms. No direct relationship between myonecrosis, thrombosis, lethality and proteolysis were observed. However, hemorrhagic activity had a good correlation with proteolytic activity, especially with hemoglobin as a substrate. © 1969.

引用

页码：175 / &

共 9 条

[1]

EMERY AJ, 1963, VENOMOUS POISONOUS A, P409

[2]

FLOWERS HERSCHEL H., 1963, TOXICON, V1, P131, DOI 10.1016/0041-0101(63)90075-8

[3]

GOUCHER CHARLES R., 1964, TOXICON, V2, P139, DOI 10.1016/0041-0101(64)90014-5

[4]

KEEGAN HL, 1963, VENOMOUS POISONOU ED, P409

[5]