DOES GALANIN INHIBIT INSULIN-SECRETION BY OPENING OF THE ATP-REGULATED K+ CHANNEL IN THE BETA-CELL

被引：37

作者：

AHREN, B

BERGGREN, PO

BOKVIST, K

RORSMAN, P

机构：

[1] LUND UNIV,DEPT SURG,S-22362 LUND,SWEDEN

[2] KAROLINSKA INST,ENDOCRINOL,S-10401 STOCKHOLM 60,SWEDEN

[3] UNIV UPPSALA,MED CELL BIOL,S-75105 UPPSALA,SWEDEN

[4] GOTHENBURG UNIV,MED PHYS,S-41124 GOTHENBURG,SWEDEN

来源：

PEPTIDES | 1989年 / 10卷 / 02期

关键词：

D O I：

10.1016/0196-9781(89)90058-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：453 / 457

页数：5

共 22 条

[1] GALANIN INHIBITS GLUCOSE-STIMULATED INSULIN RELEASE BY A MECHANISM INVOLVING HYPERPOLARIZATION AND LOWERING OF CYTOPLASMIC FREE CA-2+ CONCENTRATION
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[5] ARKHAMMAR P, 1987, J BIOL CHEM, V262, P5448
[6] GLUCOSE INDUCES CLOSURE OF SINGLE POTASSIUM CHANNELS IN ISOLATED RAT PANCREATIC BETA-CELLS
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[7] INTRACELLULAR ATP DIRECTLY BLOCKS K+ CHANNELS IN PANCREATIC B-CELLS
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[J]. NATURE, 1984, 311 (5983) : 271 - 273
[8] DEWEILLE J, 1988, P NATL ACAD SCI USA, V85, P1312
[9] GTP AND GDP ACTIVATION OF K+ CHANNELS THAT CAN BE INHIBITED BY ATP
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[J]. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1986, 407 (05): : 564 - 565
[10] GALANIN - SYMPATHETIC NEUROTRANSMITTER IN ENDOCRINE PANCREAS
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TABORSKY, GJ
[J]. DIABETES, 1988, 37 (09) : 1157 - 1162

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