RESOLUTION, ABSOLUTE-CONFIGURATION, AND ANTI-ARRHYTHMIC PROPERTIES OF THE ENANTIOMERS OF DISOPYRAMIDE, 4-(DIISOPROPYLAMINO)-2-(2-PYRIDYL)-2-PHENYLBUTYRAMIDE

被引：38

作者：

BURKE, TR

NELSON, WL

MANGION, M

HITE, GJ

MOKLER, CM

RUENITZ, PC

机构：

[1] UNIV WASHINGTON,SCH PHARM,DEPT MED CHEM,SEATTLE,WA 98195

[2] UNIV CONNECTICUT,SCH PHARM,MED CHEM & PHARMACOGNOSY SECT,STORRS,CT 06268

[3] UNIV CONNECTICUT,INST MAT SCI,STORRS,CT 06268

[4] UNIV GEORGIA,SCH PHARM,DEPT PHARMACOL,ATHENS,GA 30602

[5] UNIV GEORGIA,SCH PHARM,DEPT MED CHEM,ATHENS,GA 30602

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1980年 / 23卷 / 09期

关键词：

D O I：

10.1021/jm00183a015

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：1044 / 1048

页数：5

相关论文

共 23 条

[1] ENHANCED METABOLISM AND DIMINISHED EFFICACY OF DISOPYRAMIDE BY ENZYME-INDUCTION
AITIO, ML
VUORENMAA, T
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1980, 9 (02) : 149 - 152
[2] BAINES MW, 1976, J INT MED RES, V4, P5
[3] SCATTERING FACTORS COMPUTED FROM RELATIVISTIC DIRAC-SLATER WAVE FUNCTIONS
CROMER, DT
WABER, JT
[J]. ACTA CRYSTALLOGRAPHICA, 1965, 18 : 104 - &
[4] EFFECTS OF URINE PH AND PLASMA-PROTEIN BINDING ON RENAL CLEARANCE OF DISOPYRAMIDE
CUNNINGHAM, JL
SHEN, DD
SHUDO, I
AZARNOFF, DL
[J]. CLINICAL PHARMACOKINETICS, 1977, 2 (05) : 373 - 383
[5] DAWSON AK, 1980, FED PROC, V39, P966
[6] APPLICATION OF PHASE RELATIONSHIPS TO COMPLEX STRUCTURES .8. AN EXTENSION OF MAGIC-INTEGER APPROACH
DECLERCQ, JP
GERMAIN, G
WOOLFSON, MM
[J]. ACTA CRYSTALLOGRAPHICA SECTION A, 1975, A 31 (MAY1): : 367 - 372
[7] DESHPANDE SS, 1967, ARCH INT PHARMACOD T, V169, P55
[8] GIACOMINI KM, J CARDIOVASC PHARMAC
[9] DISOPYRAMIDE - REVIEW OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC USE IN TREATING CARDIAC-ARRHYTHMIAS
HEEL, RC
BROGDEN, RN
SPEIGHT, TM
AVERY, GS
[J]. DRUGS, 1978, 15 (05) : 331 - 368
[10] PROTEIN-BINDING AND ERYTHROCYTE PARTITIONING OF DISOPYRAMIDE AND ITS MONODEALKYLATED METABOLITE
HINDERLING, PH
BRES, J
GARRETT, ER
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1974, 63 (11) : 1684 - 1690