REVERSIBLE ENANTIOSELECTIVITY OF ENZYMATIC-REACTIONS BY MEDIA

被引：24

作者：

WU, SH ^{[1
]}

CHU, FY ^{[1
]}

WANG, KT ^{[1
]}

机构：

[1] NATL TAIWAN UNIV,DEPT CHEM,TAIPEI,TAIWAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1991年 / 1卷 / 07期

关键词：

D O I：

10.1016/S0960-894X(01)80467-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The esterification of racemic 2-(4-chlorophenoxy) propionic acid and n-butanol by the lipase from Candida cylindracea in different reaction media showed reverse enantioselectivity, pro-R enantiomer in n-hexane, isooctane, cyclohexane, toluene and aqueous phase; and pro-S in dichloromethane, acetone, n-butanol and tetrahydrofuran.

引用

页码：339 / 342

页数：4

共 21 条

[1] A SEARCH FOR PEPTIDE LIGASE - COSOLVENT-MEDIATED CONVERSION OF PROTEASES TO ESTERASES FOR IRREVERSIBLE SYNTHESIS OF PEPTIDES
BARBAS, CF
MATOS, JR
WEST, JB
WONG, CH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (15) : 5162 - 5166
[2] PREPARATIVE PRODUCTION OF OPTICALLY-ACTIVE ESTERS AND ALCOHOLS USING ESTERASE-CATALYZED STEREOSPECIFIC TRANS-ESTERIFICATION IN ORGANIC MEDIA
CAMBOU, B
KLIBANOV, AM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (09) : 2687 - 2692
[3] QUANTITATIVE-ANALYSES OF BIOCHEMICAL KINETIC RESOLUTION OF ENANTIOMERS .2. ENZYME-CATALYZED ESTERIFICATIONS IN WATER ORGANIC-SOLVENT BIPHASIC SYSTEMS
CHEN, CS
WU, SH
GIRDAUKAS, G
SIH, CJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (09) : 2812 - 2817
[4] GENERAL-ASPECTS AND OPTIMIZATION OF ENANTIOSELECTIVE BIOCATALYSIS IN ORGANIC-SOLVENTS - THE USE OF LIPASES
CHEN, CS
SIH, CJ
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1989, 28 (06): : 695 - 707
[5] QUANTITATIVE-ANALYSES OF BIOCHEMICAL KINETIC RESOLUTIONS OF ENANTIOMERS
CHEN, CS
FUJIMOTO, Y
GIRDAUKAS, G
SIH, CJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (25) : 7294 - 7299
[6] CHEN PY, 1991, THESIS NATIONAL TAIW
[7] ENANTIOSELECTIVE INHIBITION - A STRATEGY FOR IMPROVING THE ENANTIOSELECTIVITY OF BIOCATALYTIC SYSTEMS
GUO, ZW
SIH, CJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (17) : 6836 - 6841
[8] RESOLUTION OF RACEMIC MIXTURES VIA LIPASE CATALYSIS IN ORGANIC-SOLVENTS
KIRCHNER, G
SCOLLAR, MP
KLIBANOV, AM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (24) : 7072 - 7076
[9] ENZYMATIC RESOLUTION OF RACEMIC AMINES - CRUCIAL ROLE OF THE SOLVENT
KITAGUCHI, H
FITZPATRICK, PA
HUBER, JE
KLIBANOV, AM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (08) : 3094 - 3095
[10] ENZYMATIC CATALYSIS IN ANHYDROUS ORGANIC-SOLVENTS
KLIBANOV, AM
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1989, 14 (04) : 141 - 144

← 1 2 3 →