THE CHEMICAL SYNTHESIS OF LEISHMANIA-DONOVANI PHOSPHOGLYCAN FRAGMENTS

被引：18

作者：

NIKOLAEV, AV ^{[1
]}

RUTHERFORD, TJ ^{[1
]}

FERGUSON, MAJ ^{[1
]}

BRIMACOMBE, JS ^{[1
]}

机构：

[1] UNIV DUNDEE,DEPT BIOCHEM,DUNDEE DD1 4NH,SCOTLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(01)80848-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The tetraglycosyl monophosphate 1, hexaglycosyl diphosphate 2 and octaglycosyl triphosphate 3, which are fragments of the phosphoglycan portion of Leishmania donovani lipophosphoglycan, have been prepared using disaccharide H-phosphonates for construction of the phosphodiester linkages.

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页码：785 / 788

页数：4

相关论文

共 7 条

[1] SELECTIVE REMOVAL OF O-ACETYL GROUPS IN THE PRESENCE OF O-BENZOYL GROUPS BY ACID-CATALYZED METHANOLYSIS [J].

BYRAMOVA, NE ;

OVCHINNIKOV, MV ;

BACKINOWSKY, LV ;

KOCHETKOV, NK .

CARBOHYDRATE RESEARCH, 1983, 124 (01) :C8-C11

[2] SYNTHESIS OF STREPTOCOCCAL GROUP-A, GROUP-C AND VARIANT-A ANTIGENIC DETERMINANTS [J].

IVERSEN, T ;

JOSEPHSON, S ;

BUNDLE, DR .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1981, (08) :2379-2385

[3] SYNTHESIS OF LIGANDS RELATED TO THE O-SPECIFIC ANTIGEN OF TYPE-1 SHIGELLA-DYSENTERIAE .3. GLYCOSYLATION OF 4,6-O-SUBSTITUTED DERIVATIVES OF METHYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE WITH GLYCOSYL DONORS DERIVED FROM MONOSACCHARIDES AND OLIGOSACCHARIDES [J].

KOVAC, P ;

EDGAR, KJ .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (08) :2455-2467

[4] THE STEPWISE SYNTHESIS OF OLIGO(GLYCOSYL PHOSPHATES) VIA GLYCOSYL HYDROGENPHOSPHONATES - THE CHEMICAL SYNTHESIS OF OLIGOMERIC FRAGMENTS FROM HANSENULA-CAPSULATA Y-1842 EXOPHOSPHOMANNAN AND FROM ESCHERICHIA-COLI K51 CAPSULAR ANTIGEN [J].

NIKOLAEV, AV ;

IVANOVA, IA ;

SHIBAEV, VN .

CARBOHYDRATE RESEARCH, 1993, 242 :91-107

[5] ALPHA-GLYCOPYRANOSYL AND BETA-GLYCOPYRANOSYL PHOSPHATES AND 1,2-PHOSPHATES - ASSIGNMENTS OF CONFORMATIONS IN SOLUTION BY C-13 AND H-1 NMR [J].

OCONNOR, JV ;

NUNEZ, HA ;

BARKER, R .

BIOCHEMISTRY, 1979, 18 (03) :500-507

[6]

THOMAS JR, 1992, J BIOL CHEM, V267, P6829

[7] SELECTIVE ACYLATION OF PYRANOSIDES .I. BENZOYLATION OF METHYL ALPHA-D-GLYCOPYRANOSIDES OF MANNOSE GLUCOSE AND GALACTOSE [J].

WILLIAMS, JM ;

RICHARDS.AC .

TETRAHEDRON, 1967, 23 (03) :1369-&