STUDIES ON CHEMOTAXIS .X. INHIBITION OF CHEMOTAXIS OF RABBIT NEUTROPHIL POLYMORPHONUCLEAR LEUCOCYTES

被引：22

作者：

KELLER, HU

SORKIN, E

机构：

[1] Institute for Medical Research, London, NW 7, Mill Hill

[2] Schweizerisches Forschungsinstitut, Medizinische Abteilung

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1968年 / 34卷 / 05期

关键词：

D O I：

10.1159/000230145

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Inhibition of chemotaxis ofrabbit neutrophil polymorphonuclear leucocytes was studied in vitro. Cytotaxin formation in rabbit serum induced by antigen-antibody complexes was inhibited by 0.05 M N-CBZ-glycyl-L-phenylalanine, but not by 0.06 m ɛ-amino carpoic acid. N-CBZ- a-glutamyl-L-tyrosine failed to inactivate antigen-antibody treated serum. Polymorphs were found to be susceptible to repeated chemotactic stimulation, but incubation with washed immune complexes results in reduced responsiveness. © 1968 S. Karger AG, Basel.

引用

页码：513 / &

共 17 条

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KELLER, HU
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[10] KELLER HU, 1965, IMMUNOLOGY, V9, P441

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