STRUCTURE OF TETRAMYCIN, A NEW POLYENE MACROLIDE ANTIBIOTIC

被引：10

作者：

DORNBERGER, K ^{[1
]}

THRUM, H ^{[1
]}

RADICS, L ^{[1
]}

机构：

[1] HUNGARIAN ACAD SCI, CENT RES INST CHEM, NMR LAB, H-1025 BUDAPEST, HUNGARY

来源：

TETRAHEDRON | 1979年 / 35卷 / 15期

关键词：

D O I：

10.1016/0040-4020(79)80009-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structure of the tetraene antifungal antibiotic tetramycin was established by detailed studies of mass, 1H and 13C NMR spectra and by chemical degradation. A newly developed mass analysis was introduced for determining the C skeleton of the aglycone.

引用

页码：1851 / 1856

页数：6

共 17 条

[1]

ARDENNE MV, 1971, ELEKTRONENANLAGERUNG

[2] PIMARICIN .6. COMPLETE STRUCTURE OF ANTIBIOTIC [J].

CEDER, O .

ACTA CHEMICA SCANDINAVICA, 1964, 18 (01) :126-&

[3] PIMARICIN .8. STRUCTURAL AND CONFIGURATIONAL STUDIES BY ELECTRON-IMPACT AND FIELD DESORPTION MASS-SPECTROMETRY, C-13 (25.2 MHZ) AND H-1 (270 MHZ)-NMR SPECTROSCOPY [J].

CEDER, O ;

HANSSON, B ;

RAPP, U .

TETRAHEDRON, 1977, 33 (20) :2703-2714

[4] FUNGICHROMIN - COMPLETE STRUCTURE AND ABSOLUTE CONFIGURATION AT C26 AND C27 [J].

COPE, AC ;

GILLIS, BT ;

JOHNSON, HE ;

CIGANEK, E ;

CEDER, OJ ;

BURROWS, EP ;

BLY, RK ;

PORTER, F .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1962, 84 (11) :2170-&

[5] TETRAMYCIN, A NEW POLYENE ANTIBIOTIC [J].

DORNBERGER, K ;

FUGNER, R ;

BRADLER, G ;

THRUM, H .

JOURNAL OF ANTIBIOTICS, 1971, 24 (03) :172-+

[6]

DORNBERGER K, 1976, TETRAHEDRON LETT, P4469

[7] MASS-SPECTROSCOPY OF POLYENE ANTIBIOTICS - FRAGMENTATION BEHAVIOR OF TETRAENES [J].

DORNBERGER, K ;

VOIGT, D ;

IHN, W ;

VOKOUN, J ;

THRUM, H .

TETRAHEDRON, 1976, 32 (24) :3069-3073

[8]

GAUDIANO G, 1966, TETRAHEDRON LETT, P3567

[9] STUDIES ON BIOSYNTHESIS OF 16-MEMBERED MACROLIDE ANTIBIOTICS USING C-13 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY [J].

OMURA, S ;

TAKESHIMA, H ;

NAKAGAWA, A ;

MIYAZAWA, J ;

PIRIOU, F ;

LUKACS, G .

BIOCHEMISTRY, 1977, 16 (13) :2860-2866

[10]

OROSHNIK W, 1963, FORTSCHR CHEM ORG NA, V21, P18

← 1 2 →