NUCLEAR TARGETING SEQUENCES - A CONSENSUS

被引：1839

作者：

DINGWALL, C

LASKEY, RA

机构：

[1] Wellcome Trust/Cancer Research Campaign Institute of Cancer and Developmental Biology, Cambridge, Tennis Court Road

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 12期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0968-0004(91)90184-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nuclear targeting sequences are essential for the transport of proteins into the nucleus. The seven-amino-acid nuclear targeting sequence of the SV40 large T antigen has been regarded as the model; however, many nuclear targeting sequences appear to be more complex. We suggest in this review that, despite this diversity, a consensus bipartite motif can be identified.

引用

页码：478 / 481

页数：4

共 35 条

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