CENTRAL NORADRENERGIC REACTIVITY TO STRESS IN MAUDSLEY RAT STRAINS

被引：18

作者：

BUDA, M

LACHUER, J

DEVAUGES, V

BARBAGLI, B

BLIZARD, D

SARA, SJ

机构：

[1] UNIV PARIS 06,INST NEUROSCI,CNRS,URA 1488,F-75005 PARIS,FRANCE

[2] CTR HOSP LYON SUD,INSERM,U171,PIERRE BENITE,FRANCE

[3] CTR HOSP LYON SUD,NEUROCHIM FONCT LAB,CNRS,URA 1195,PIERRE BENITE,FRANCE

[4] PENN STATE UNIV,CTR HLTH & DEV GENET,UNIV PK,PA

来源：

NEUROSCIENCE LETTERS | 1994年 / 167卷 / 1-2期

关键词：

IMMOBILIZATION; STRESS; LOCUS COERULEUS; NORADRENALINE; 3,4-DIHYDROXYPHENYLACETIC ACID; MAUDSLEY RAT STRAIN;

D O I：

10.1016/0304-3940(94)91021-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Maudsley reactive (MR) and Maudsley nonreactive (MNRA) rats were submitted to a single session of acute 5-min immobilization stress and immediately sacrificed by decapitation. Subsequent neurochemical analysis revealed an elevation of 3,4-dihydroxyphenylacetic acid levels in the locus coeruleus and in the ventrolateral medulla, but not in the dorsomedial medulla, of rats of the two strains compared with nonstressed controls; This response was greater in the MR than in the MNRA group, suggesting a strain difference in the reactivity of the central noradrenergic cells to acute stress.

引用

页码：33 / 36

页数：4

共 24 条

[1] BEHAVIOR AND CORTICOSTEROID RESPONSE OF MAUDSLEY REACTIVE AND NONREACTIVE RATS IN THE OPEN-FIELD AND FORCED SWIMMING TEST
ABEL, EL
[J]. PHYSIOLOGY & BEHAVIOR, 1991, 50 (01) : 151 - 153
[2] AMARAL DG, 1977, PROG NEUROBIOL, V9, P146
[3] Aston-Jones G., 1990, PHARM NORADRENALINE, P187
[4] THE LOCUS CERULEUS - A POSSIBLE NEURAL FOCUS FOR GENETIC-DIFFERENCES IN EMOTIONALITY
BLIZARD, DA
[J]. EXPERIENTIA, 1988, 44 (06): : 491 - 495
[5] THE MAUDSLEY REACTIVE AND NON-REACTIVE STRAINS - A NORTH-AMERICAN PERSPECTIVE
BLIZARD, DA
[J]. BEHAVIOR GENETICS, 1981, 11 (05) : 469 - 489
[6] GENETIC-VARIATION, CHRONIC STRESS, AND THE CENTRAL AND PERIPHERAL NORADRENERGIC SYSTEMS
BLIZARD, DA
FREEDMAN, LS
LIANG, B
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1983, 245 (04): : R600 - R605
[7] MAUDSLEY REACTIVE AND NONREACTIVE STRAINS OF RATS - SURVEY
BROADHURST, PL
[J]. BEHAVIOR GENETICS, 1975, 5 (04) : 299 - 319
[8] INCREASE IN TYROSINE-HYDROXYLASE ACTIVITY IN LOCUS COERULEUS OF RAT-BRAIN AFTER CONTRALATERAL LESIONING
BUDA, M
ROUSSEL, B
RENAUD, B
PUJOL, JF
[J]. BRAIN RESEARCH, 1975, 93 (03) : 564 - 569
[9] ACTIVATION OF LOCUS COERULEUS NEURONS BY PERIPHERAL STIMULI - MODULATION BY A COLLATERAL INHIBITORY MECHANISM
CEDARBAUM, JM
AGHAJANIAN, GK
[J]. LIFE SCIENCES, 1978, 23 (13) : 1383 - 1392
[10] THE FORMATION OF DEAMINATED METABOLITES OF DOPAMINE IN THE LOCUS COERULEUS DEPENDS UPON NORADRENERGIC NEURONAL-ACTIVITY
CURET, O
DENNIS, T
SCATTON, B
[J]. BRAIN RESEARCH, 1985, 335 (02) : 297 - 301

← 1 2 3 →