PROTON NUCLEAR MAGNETIC-RESONANCE EVIDENCE FOR THE ABSENCE OF A STABLE HYDROGEN-BOND BETWEEN THE ACTIVE-SITE ASPARTATE AND HISTIDINE-RESIDUES OF NATIVE SUBTILISINS AND FOR ITS PRESENCE IN THIOLSUBTILISINS

被引：25

作者：

JORDAN, F ^{[1
]}

POLGAR, L ^{[1
]}

机构：

[1] HUNGARIAN ACAD SCI,BIOL RES CTR,INST ENZYMOL,H-1502 BUDAPEST,HUNGARY

来源：

BIOCHEMISTRY | 1981年 / 20卷 / 22期

关键词：

D O I：

10.1021/bi00525a013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：6366 / 6370

页数：5

共 22 条

[1] N-15 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY - STATE OF HISTIDINE IN CATALYTIC TRIAD OF ALPHA-LYTIC PROTEASE - IMPLICATIONS FOR CHARGE-RELAY MECHANISM OF PEPTIDE-BOND CLEAVAGE BY SERINE PROTEASES
BACHOVCHIN, WW
ROBERTS, JD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (26) : 8041 - 8047
[2] ROLE OF A BURIED ACID GROUP IN MECHANISM OF ACTION OF CHYMOTRYPSIN
BLOW, DM
BIRKTOFT, JJ
HARTLEY, BS
[J]. NATURE, 1969, 221 (5178) : 337 - &
[3] CORRELATION NMR-SPECTROSCOPY
DADOK, J
SPRECHER, RF
[J]. JOURNAL OF MAGNETIC RESONANCE, 1974, 13 (02) : 243 - 248
[4] TISSUE SULFHYDRYL GROUPS
ELLMAN, GL
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1959, 82 (01) : 70 - 77
[5] CARBON NUCLEAR MAGNETIC-RESONANCE STUDIES OF HISTIDINE RESIDUE IN ALPHA-LYTIC PROTEASE - IMPLICATIONS FOR CATALYTIC MECHANISM OF SERINE PROTEASES
HUNKAPILLER, MW
SMALLCOMBE, SH
WHITAKER, DR
RICHARDS, JH
[J]. BIOCHEMISTRY, 1973, 12 (23) : 4732 - 4743
[6] NEUTRON-DIFFRACTION IDENTIFIES HIS-57 AS THE CATALYTIC BASE IN TRYPSIN
KOSSIAKOFF, AA
SPENCER, SA
[J]. NATURE, 1980, 288 (5789) : 414 - 416
[7] SERINE PROTEASES - STRUCTURE AND MECHANISM OF CATALYSIS
KRAUT, J
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1977, 46 : 331 - 358
[8] HYDROGEN-BONDS IN SERINE PROTEINASES AND THEIR COMPLEXES WITH PROTEIN PROTEINASE-INHIBITORS PROTON NUCLEAR MAGNETIC-RESONANCE STUDIES
MARKLEY, JL
[J]. BIOCHEMISTRY, 1978, 17 (22) : 4648 - 4656
[9] CHARGE-RELAY SYSTEM OF SERINE PROTEINASES - PROTON MAGNETIC-RESONANCE TITRATION STUDIES OF 4 HISTIDINES OF PORCINE TRYPSIN
MARKLEY, JL
PORUBCAN, MA
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1976, 102 (03) : 487 - 509
[10] MATTHEWS DA, 1977, J BIOL CHEM, V252, P8875

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