PARAPROTEINEMIA AND CRYOGLOBULINEMIA ASSOCIATED WITH ATYPICAL GLOMERULONEPHRITIS AND NEPHROTIC SYNDROME

被引：46

作者：

PORUSH, JG

GRISHMAN, E

ALTER, AA

MANDELBAUM, H

CHURG, J

机构：

来源：

AMERICAN JOURNAL OF MEDICINE | 1969年 / 47卷 / 06期

关键词：

D O I：

10.1016/0002-9343(69)90208-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A patient with an atypical from of glomerulonephritis and the nephrotic syndrome, whose serum contained a paraprotein and mixed cryoglobulin and had rheumatoid factor activity, is described. The nephritis was characterized by the presence of numerous intracellular crystals, wire loops and hyaline thrombi in the glomeruli. It appears reasonable to assume that the crystals and other deposits represent precipitated protein, probably related to the paraprotein and cryoglobulin in the serum. It is suggested that the crystals are derived from the paraprotein and that the mixed cryoglobulins (possibly antigen-antibody complexes) give rise to the deposits seen along the basement membrane. © 1969.

引用

页码：957 / +

页数：1

共 18 条

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