MUTUAL INFLUENCE OF GASTRIN AND SECRETIN ON THE EXTERNAL PANCREATIC SECRETION IN DOGS

被引:18
作者
HENRIKSEN, FW
WORNING, H
机构
[1] Institute of Experimental Research in Surgery, University of Copenhagen, Central Laboratorium, Blegdamshospital, Medical Department P, Rigshospitalet, Copenhagen
来源
ACTA PHYSIOLOGICA SCANDINAVICA | 1969年 / 76卷 / 1-2期
关键词
D O I
10.1111/j.1748-1716.1969.tb04451.x
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The external pancreatic secretion of fluid, bicarbonate and protein in 4 dogs with Thomas type fistulae, has been studied in response to secretin (1 U/kg b.w.), gastrin (2 U/kg b.w.) and combined secretin–gastrin stimulation. Gastrin exerted a stimulating effect on the pancreatic secretion of fluid, bicarbonate and protein and increased the bicarbonate concentration in the juice significantly above basal level. The combined effect of secretin and gastrin on the secretion of fluid, bicarbonate and protein did not differ from the summarized effect of the two agents given separately. Potentation between secretin and gastrin was not demonstrated. © 1969 Scandinavian Physiological Society
引用
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页码:67 / +
页数:1
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