PARTITIONING OF OXAMNIQUINE INTO BRAIN-TISSUE FOLLOWING INTRAVENOUS ADMINISTRATION TO FEMALE WISTAR RATS

被引：26

作者：

KOKWARO, GO

TAYLOR, G

机构：

[1] Welsh School of Parmacy, University of Wales College of Cardiff, Cardiff, CF1 3XF, Great Britain

来源：

DRUG AND CHEMICAL TOXICOLOGY | 1990年 / 13卷 / 04期

关键词：

D O I：

10.3109/01480549009032291

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Brain and plasma concentrations of oxamniquine were determined following intravenous dosing (15 mg kg1) in female Wistar rats. Maximum brain concentrations were achieved one hour after dosing and at all sampling times oxamniquine levels were higher in brain tissues compared to the corresponding plasma samples. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：347 / 354

页数：8

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