DIFFERENTIAL DOWN-REGULATION OF ESTROGEN RECEPTOR-LIKE IMMUNOREACTIVITY BY ESTRADIOL IN THE FEMALE BRAZILIAN OPOSSUM BRAIN

被引：13

作者：

PEARSON, PL

ROSS, LR

JACOBSON, CD

机构：

[1] IOWA STATE UNIV SCI & TECHNOL,DEPT VET ANAT,AMES,IA 50011

[2] IOWA STATE UNIV SCI & TECHNOL,MOLEC CELLULAR & DEV BIOL PROGRAM,AMES,IA 50011

来源：

BRAIN RESEARCH | 1993年 / 617卷 / 01期

关键词：

MARSUPIAL; STEROID RECEPTOR; MEDIAL PREOPTIC AREA; MONODELPHIS; LIMBIC SYSTEM; REPRODUCTION; SEPTUM;

D O I：

10.1016/0006-8993(93)90632-W

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (Monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovariectomized controls. These results support a down-regulatory role for estrogen in relation to its receptor in the brain, and indicate that ER-LI is differentially regulated in the Monodelphis forebrain.

引用

页码：171 / 175

页数：5

共 24 条

[1]

BAGGOTT LM, 1987, J REPROD FERTIL, V79, P105

[2]

BECKER JB, 1992, BEHAVIORAL ENDOCRINO, P53

[3] ESTROGEN RECEPTOR-IMMUNOSTAINING OF NEURONAL CYTOPLASMIC PROCESSES AS WELL AS CELL-NUCLEI IN GUINEA-PIG BRAIN [J].