EFFECT OF MILD EXERCISE ON GLUCOSE UPTAKE IN HUMAN FOREARM TISSUES IN FASTING STATE AND AFTER ORAL GLUCOSE ADMINISTRATION

Peripheral glucose uptake was found to be comparable in the right and left arms at rest in fasting non-diabetic and diabetic subjects. In the fasting state, glucose uptake and blood flow in the exercising arm was higher than in the resting arm. Following the oral administration of 50 Gm. glucose, glucose uptake rose both in the resting limb and, to an even greater extent, in the exercising limb in the non-diabetic subjects. In the diabetics, the findings were variable, and no effect of exercise could be detected in 2 insulin-dependent diabetics deprived of insulin The mechanism of action of the exercise effect and its dependence on circulating insulin is discussed. © 1968.