MALIGNANT TRANSFORMATION OF ECCRINE TUMORS

被引：72

作者：

GALADARI, E

MEHREGAN, AH

LEE, KC

机构：

[1] WAYNE STATE UNIV, SCH MED, DEPT DERMATOL & SYPHILOL, DETROIT, MI 48201 USA

[2] QUEEN ELIZABETH HOSP, HONG KONG, HONG KONG

来源：

JOURNAL OF CUTANEOUS PATHOLOGY | 1987年 / 14卷 / 01期

关键词：

D O I：

10.1111/j.1600-0560.1987.tb00122.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Malignant transformation occurred in pre-existing sweat gland tumors in 7 patients. Three lesions showed a histologic pattern of ecrrine spiradenoma, 2 eccrine poroma, one cylindroma and one papillary eccrine adenoma. Malignant transformation was histologically characterized by the presence of solid tumor areas populated with large cells having irregularly shaped nuclei and mitotic figures. There were multiple foci of squamous metaplasia, areas of loss of basement membrane and invasion of the surrounding connective tissue.

引用

页码：15 / 22

页数：8

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