MUTAGENIC EFFECTS OF CADMIUM ON MAMMALIAN OOCYTE CHROMOSOMES

被引：63

作者：

WATANABE, T

SHIMADA, T

ENDO, A

机构：

[1] Department of Hygiene and Preventive Medicine, Yamagata University School of Medicine, Yamagata

来源：

MUTATION RESEARCH | 1979年 / 67卷 / 04期

关键词：

D O I：

10.1016/0165-1218(79)90031-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

When female golden hamsters were treated with cadmium chloride at the oogenesis stages of diakinesis/metaphase I to metaphase II, oocytes with the chromosomal complements of hyperhaploidy and diploidy, as well as oocytes at the anaphase-I stage, were observed. Oocytes of this species were especially sensitive to cadmium. Chromosome analysis of metaphase-II oocytes seems to be a useful method for the screening of mutagenicity of environmental contaminants in mammalian germ cells in vivo. © 1979.

引用

页码：349 / 356

页数：8

共 31 条

[1] CHROMOSOME-ABERRATIONS IN LYMPHOCYTES AFTER OCCUPATIONAL EXPOSURE TO LEAD AND CADMIUM [J].