VIMENTIN EXPRESSION BY REED-STERNBERG CELLS IN HODGKINS-DISEASE

被引：6

作者：

ANGEL, CA

CULLEN, RA

PRINGLE, JH

LAUDER, I

机构：

[1] UNIV LEICESTER,LEICESTER ROYAL INFIRM,DEPT PATHOL,LEICESTER LE1 7RH,ENGLAND

[2] LEICESTER ROYAL INFIRM,DEPT HISTOPATHOL,LEICESTER LE2 7LX,ENGLAND

来源：

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1992年 / 421卷 / 01期

关键词：

VIMENTIN; REED-STERNBERG CELLS; HODGKINS DISEASE; IMMUNOHISTOLOGY;

D O I：

10.1007/BF01607132

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The expression of vimentin in Reed-Sternberg cells in 61 samples of Hodgkin's disease (HD) was examined using an avidin-biotin-peroxidase complex technique. Forty biopsies (66%) expressed vimentin, and expression was seen in all subtypes of HD. No immunophenotypic differences between vimentin-positive and vimentin-negative cases were noted. The significance of such expression is unclear, but may be related to the alterations in growth and differentiation that are typical of neoplastic cells.

引用

页码：9 / 11

页数：3

共 24 条

[11] A MONOCLONAL-ANTIBODY (MMA) THAT IDENTIFIES A DIFFERENTIATION ANTIGEN ON HUMAN MYELOMONOCYTIC CELLS [J].