EFFECT OF DOPALANINE ON BEHAVIOUR IN MICE DEPLETED OF NOREPINEPHRINE OR SEROTONIN

被引:30
作者
CHRUSCIE.TL
HERMAN, ZS
机构
[1] Department of Pharmacology, Silesian School of Medicine
来源
PSYCHOPHARMACOLOGIA | 1969年 / 14卷 / 02期
关键词
α-Methyltyrosine; Behaviour; Dopalanine; Mice; p-Chlorophenylalanine;
D O I
10.1007/BF00403685
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
These studies were performed to investigate the behavioral and biochemical effects of DOPA in mice which had undergone selective depletion of NE or 5-HT. PCPA caused an increase of locomotor activity and DOPA potentiated this effect. α-MT inhibited locomotor activity and DOPA had no consistent effect on locomotor activity which had been inhibited in this way. DOPA caused a transient increase of locomotor activity. These behavioral changes are discussed in relation to biochemical changes observed in the brain. © 1969 Springer-Verlag.
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页码:124 / &
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