NITRIC-OXIDE PRODUCTION DOES NOT DIRECTLY INCREASE MACROPHAGE CANDIDACIDAL ACTIVITY

被引：38

作者：

VAZQUEZTORRES, A

JONESCARSON, J

BALISH, E

机构：

[1] UNIV WISCONSIN,SCH MED,DEPT SURG,MADISON,WI 53706

[2] UNIV WISCONSIN,SCH MED,DEPT MED MICROBIOL & IMMUNOL,MADISON,WI 53706

来源：

INFECTION AND IMMUNITY | 1995年 / 63卷 / 03期

关键词：

D O I：

10.1128/IAI.63.3.1142-1144.1995

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Some activated murine macrophages produced nitrite but were unable to kill Candida albicans. Furthermore, a nitric oxide (NO) generator inhibited C. albicans growth but was not candidacidal. Our results suggest that NO is candidastatic and that NO is not directly involved but is associated with or induces other macrophage candidacidal mechanisms.

引用

页码：1142 / 1144

页数：3

共 15 条

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