POTENTIAL ANTIDIABETICS .3. 4-ARYLHYDRAZONO-1-CARBAMOYL-3-METHYL-2-PYRAZOLIN-5-ONES AND 4-ARYLAZO-1-(2,4-DINITROPHENYL)-3-METHYL-5-PHENYLPYRAZOLES

被引：35

作者：

GARG, HG

SINGH, PP

机构：

[1] Department of Chemistry, University of Roorkee, Roorkee

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 08期

关键词：

D O I：

10.1039/j39690001141

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 4-arylhydrazono-1-carbarnoyl-3-methyl-2-pyrazolin-5-ones have been synthesised, for evaluation as antidiabetic agents, from the appropriate aryldiazonium salts and 1-carbamoyl-3-methyl-2-pyrazolin-5-one. A series of 4-arylazo-1-(2,4-dinitrophenyl)-3-methyl-5-phenylpyrazoles were obtained by the cyclisation of 2-arylhydrazono-1-phenylbutane-1,2,3-triones with 2,4-dinitrophenylhydrazine.

引用

页码：1141 / &

共 9 条

[1] DE SC, 1926, Q J INDIAN CHEM SOC, V3, P30
[2] DULIN WE, 1966, P SOC EXP BIOL MED, V121, P777
[3] PHARMACOLOGY AND MODE OF ACTION OF HYPOGLYCAEMIC SULPHONYLUREAS AND DIGUANIDES
DUNCAN, LJP
CLARKE, BF
[J]. ANNUAL REVIEW OF PHARMACOLOGY, 1965, 5 : 151 - &
[4] Garg H G, 1968, J Med Chem, V11, P1103, DOI 10.1021/jm00311a057
[5] POTENTIAL ANTIDIABETICS .2. I-(2,4-DINITROPHENYL)-3-METHYL-4-ARYLAZO-2-PYRAZOLIN-5-ONES
GARG, HG
SINGH, PP
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (05) : 1104 - &
[6] Garg HG, 1960, J INDIAN CHEM SOC, V37, P626
[7] GARG HG, 1959, THESIS AGRA U
[8] GERRITSEN GC, 1965, J PHARMACOL EXP THER, V150, P491
[9] INSULIN AND PANCREAS
GRODSKY, GM
FORSHAM, PH
[J]. ANNUAL REVIEW OF PHYSIOLOGY, 1966, 28 : 347 - &

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