EFFECTS OF FE3+-TUMOR CELL-INTERACTION ON CA2+-UPTAKE BY EHRLICH ASCITES TUMOR-CELLS

被引:32
作者
ANGHILERI, LJ
机构
[1] Biophysics Laboratory, Medicine Faculty, University of Nancy, Nancy
关键词
D O I
10.1016/0143-4160(91)90053-H
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Fe3+ ions complexed by various ligands induce an increased Ca2+ uptake by Ehrlich carcinoma ascites cells that is proportional to the thermodynamic stability constant of the complex, and the greatest increase is observed with ferric lactate. The absence of ATPase inhibition showed by this ferric complex, suggests that an increased passive diffusion of Ca2+ due to structural modifications of the cell membrane is the most probable cause of this phenomenon.
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页码:371 / 374
页数:4
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