SUPERWARFARIN INGESTION AND DETECTION

被引:32
作者
ROUTH, CR
TRIPLETT, DA
MURPHY, MJ
FELICE, LJ
SADOWSKI, JA
BOVILL, EGT
机构
[1] BALL MEM HOSP,DEPT PATHOL,MUNCIE,IN 47303
[2] UNIV MINNESOTA,COLL VET MED,DEPT VET DIAGNOST INVEST,MINNEAPOLIS,MN 55455
[3] TUFTS UNIV,USDA,HUMAN NUTR RES CTR AGING,BOSTON,MA 02111
[4] UNIV VERMONT,DEPT PATHOL,BURLINGTON,VT 05405
关键词
SUPERWARFARIN COMPOUNDS; BRODIFACOUM; RODENTICIDES; 2ND-GENERATION ANTICOAGULANT RODENTICIDES; VITAMIN-K;
D O I
10.1002/ajh.2830360111
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Because of the emergence of warfarin resistance, new potent long-acting anticoagulants are now readily available in several over-the-counter rodenticide products. The availability of these "superwarfarin" compounds has led to accidental and purposeful human ingestions, one of which has resulted in a death. We summarize the prior case reports and report a second death. In addition, we report the availability of an assay to detect the presence of brodifacoum (a superwarfarin compound) in human plasma and tissues.
引用
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页码:50 / 54
页数:5
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