THE AGE-DEPENDENT RISK OF POSTVACCINATION COMPLICATIONS IN VACCINEES WITH SMALLPOX VACCINE

被引：23

作者：

GURVICH, EB

机构：

[1] The State Research Institute of Standardization and Control of Medical Biologics, Moscow

来源：

VACCINE | 1992年 / 10卷 / 02期

关键词：

VACCINIA; POSTVACCINATION COMPLICATIONS; NEUROLOGICAL; DERMAL; RECOMBINANT VACCINIA VACCINE;

D O I：

10.1016/0264-410X(92)90023-D

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The use of vaccinia virus in recombinant systems may result in the occurrence of complications observed following smallpox vaccination. The results are presented of a large survey carried out in the USSR between 1968 and 1979. High complication rates are reported, particularly in older primary vaccinees; for example, there were 312.5 cases of neurological complications per million in those aged greater-than-or-equal-to 5 years. The author concludes that this factor will limit the use of vaccinia virus in recombinant technology.

引用

页码：96 / 97

页数：2

共 9 条

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