BONY AND VASCULAR ANATOMY OF THE NORMAL CERVICAL-SPINE IN THE SHEEP

被引:31
作者
CAIN, CCMJ
FRASER, RD
机构
[1] Spinal Unit, The Department of Orthopaedic Surgery and Trauma, Royal Adelaide Hospital, Adelaide
关键词
ANATOMY; ANIMAL; ANIMAL MODEL; SPINAL CORD;
D O I
10.1097/00007632-199504000-00002
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study Design. This study analyzed the vascular and skeletal anatomy of the sheep cervical spine. It discusses comparative anatomy of the cervical spine of sheep and humans. Objectives. To establish the suitability of the sheep model for studying the pathophysiology of traumatic and degenerative conditions of the cervical spine. Summary of Background Data. Many studies have attempted to evaluate the pathophysiology of spinal cord trauma, hypoxia, and variations in the local environment of the spinal cord using a variety of animal models. Few of the studies identified in an extensive literature review report or comment on the validity:of these models regarding anatomy. Methods. Techniques of macro- and micro-dissection and vascular casting with latex and methyl-methacrylate were emplpyed and the anatomy. of sheep was compared with that of humans. Results. On an anatomical basis, we found the sheep to be a suitable model for studying the pathophysiology of spinal cord trauma and disorders relative to humans. Conclusions. To properly assess the effect of various pathological processes on the spinal cord, an anatomically valid model is required. This study established that the sheep is a suitable animal model for studies of this type.
引用
收藏
页码:759 / 765
页数:7
相关论文
共 39 条
[1]  
Adamkiewicz A.A., Die Blutgefässe des menschlichen Rückenmarkes. I. Die Gefasse der Ruckenmarks-substanz, Sit-Zungsber Akad Wiss Wien Math-Naturwiss KL, 84, pp. 469-502, (1882)
[2]  
Adamkiewicz A.A., Die Blutgefässe des menschlichen Rückenmarkes. II. Die Gefasse der Ruckenmarks-substanz, Sitzungsber Akad Wiss Wien Math-Naturwiss. KL, 85, pp. 101-130, (1882)
[3]  
Bennett M.H., Effects of compression and ischemia on spinal cord evoked potentials, Exp Neurol, 80, pp. 508-509, (1983)
[4]  
Black P., Markowitz R.S., Cooper V., Et al., Models of spinal cord injury: Part 1. Static load technique, Neurosurgery, 19, pp. 752-762, (1986)
[5]  
Black P., Markowitz R.S., Damjanov I., Et al., Models of spinal cord injury: Part 3. Dynamic load technique, Neurosurgery, 22, pp. 51-60, (1988)
[6]  
Cain C., Langston P.G., Weston P.F., Fraser R.D., Assessment of spinal cord blood flow and function in sheep following antero-lateral cervical interbody fusion in the presence of cord damage, Spine, 19, pp. 511-519, (1994)
[7]  
Cheng M., Robertson C., Grossman R.G., Foltz R., Williams V., Neurological outcome correlated with spinal evoked potentials in a spinal cord ischaemia model, J Neurosurg, 60, pp. 786-795, (1984)
[8]  
Crock H.V., Yoshizawa H., The Blood Supply of the Vertebral Column and Spinal Cord in Man, (1977)
[9]  
Croft T.L., Brodkey J.S., Nulsen F.E., Reversible spinal cord trauma: A model for electrical monitoring of spinal cord function, J Neurosurg, 36, pp. 402-406, (1972)
[10]  
Dohrmann G.J., Wagner F.C., Bucy P.C., The microvasculature in transitory traumatic paraplegia. An electron microscopic study in the monkey, J Neurosurg, 35, pp. 263-271, (1971)