INCREASED ASSOCIATION OF RIBOSOMES WITH MYOFIBRILS DURING THE SKELETAL-MUSCLE HYPERTROPHY INDUCED EITHER BY THE BETA-ADRENOCEPTOR AGONIST CLENBUTEROL OR BY TENOTOMY

被引：28

作者：

HORNE, Z ^{[1
]}

HESKETH, J ^{[1
]}

机构：

[1] ROWETT RES INST,DIV BIOCHEM SCI,GREENBURN RD,BUCKSBURN AB2 9SB,ABERDEEN,SCOTLAND

来源：

BIOCHEMICAL JOURNAL | 1990年 / 272卷 / 03期

关键词：

D O I：

10.1042/bj2720831

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ribosome distribution in skeletal-muscle myofibres was investigated by immunohistochemistry and microdensitometry by using anti-(60 S ribosomal subunit) antibodies. Administration of the beta-adrenoceptor agonist clenbuterol caused an increase in the staining of the myofibrillar region with this antibody relative to that found in the subsarcolemmal cytoplasm. A similar effect was observed during hypertrophy of the plantaris muscle following severance of the tendon to the gastrocnemius. The results suggest that increased association of ribosomes with the myofibrils occurs during muscle hypertrophy.

引用

页码：831 / 833

页数：3

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