GAMMA-PROBE GUIDED LOCALIZATION OF LYMPH-NODES

被引:271
作者
ALEX, JC [1 ]
KRAG, DN [1 ]
机构
[1] UNIV VERMONT,DEPT SURG,GIVEN BLDG,BURLINGTON,VT 05405
来源
SURGICAL ONCOLOGY-OXFORD | 1993年 / 2卷 / 03期
关键词
GAMMA-PROBE; LYMPH NODE; MELANOMA; TECHNETIUM;
D O I
10.1016/0960-7404(93)90001-F
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The initial draining lymph node (Sentinel node) of a tumour may reflect the status of the tumours spread to the remaining lymphatic bed. The sentinel node, which has been reported to predict metastatic melanoma, has recently been localized by a new invasive technique [1]. The goal of our pre-clinical trial was to test a non-invasive technique to localize the sentinel node. Gamma-probe guided localization was used to identify and then surgically remove the first draining lymph node(s) in 16 inguinal lymphatic basins of eight cats. This method was found to be comparable to an invasive method using a blue dye. Gamma-probe localization has several potential advantages in that it can: (a) precisely locate on the surface of the skin the position of an underlying lymph node, (b) intraoperatively guide the surgeon to the lymph node during dissection, (c) verify that the correct node has been biopsied, (d) determine the possible presence of residual lymph nodes, (e) allow lymph nodes to be harvested through a small incision as opposed to raising a skin flap, and (f) be rapidly and easily performed. Surgical
引用
收藏
页码:137 / 143
页数:7
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