ACTIVATION OF DIHALOALKANES BY GLUTATHIONE CONJUGATION AND FORMATION OF DNA ADDUCTS

被引：33

作者：

GUENGERICH, FP ^{[1
]}

PETERSON, LA ^{[1
]}

CMARIK, JL ^{[1
]}

KOGA, N ^{[1
]}

INSKEEP, PB ^{[1
]}

机构：

[1] VANDERBILT UNIV,MED CTR,SCH MED,CTR MOLEC TOXICOL,NASHVILLE,TN 37232

来源：

ENVIRONMENTAL HEALTH PERSPECTIVES | 1987年 / 76卷

关键词：

D O I：

10.2307/3430459

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

引用

页码：15 / 18

页数：4

共 23 条

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GREEN, T .

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[3]

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[4] INVITRO ACTIVATION OF 1,2-DICHLOROETHANE BY MICROSOMAL AND CYTOSOLIC ENZYMES [J].

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MACDONALD, TL ;

WATANABE, PG .

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[5]

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[6] GLUTATHIONE-MEDIATED BINDING OF DIBROMOALKANES TO DNA - SPECIFICITY OF RAT GLUTATHIONE-S-TRANSFERASES AND DIBROMOALKANE STRUCTURE [J].

INSKEEP, PB ;

GUENGERICH, FP .

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[7] MUTAGENIC EFFECT OF DICHLOROMETHANE ON SALMONELLA-TYPHIMURIUM [J].

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MUTATION RESEARCH, 1978, 56 (03) :245-248

[8]

KOGA N, 1986, BIOCHEMISTRY-US, V25, P2192, DOI 10.1021/bi00356a051

[9] 2 FATALITIES AFTER ACUTE OCCUPATIONAL EXPOSURE TO ETHYLENE DIBROMIDE [J].

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WADE, RL ;

BECKER, CE .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1984, 252 (17) :2428-2431

[10] IDENTIFICATION OF AN ACTIVATED C-KI-RAS ONCOGENE IN RAT-LIVER TUMORS INDUCED BY AFLATOXIN-B1 [J].

MCMAHON, G ;

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WOGAN, GN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (24) :9418-9422

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