RADIATION MYELITIS - A COMPLICATION OF CONCURRENT CISPLATIN AND 5-FLUOROURACIL CHEMOTHERAPY WITH EXTENDED FIELD RADIOTHERAPY FOR CARCINOMA OF THE UTERINE CERVIX

被引：12

作者：

BLOSS, JD

DISAIA, PJ

MANNEL, RS

HYDEN, EC

MANETTA, A

WALKER, JL

BERMAN, ML

机构：

[1] UNIV CALIF IRVINE, IRVINE MED CTR, DIV RADIAT ONCOL, ORANGE, CA 92668 USA

[2] UNIV OKLAHOMA, HLTH SCI CTR, DIV GYNECOL ONCOL, OKLAHOMA CITY, OK 73190 USA

来源：

GYNECOLOGIC ONCOLOGY | 1991年 / 43卷 / 03期

关键词：

D O I：

10.1016/0090-8258(91)90041-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Radiation myelitis is a rare but serious complication of radiation therapy. The total dose of radiation to the spinal cord required to cause myelopathy is greater than 50 Gy when the treatment is administered in 25 or more fractions; however, recent evidence has suggested that the concurrent use of chemotherapy may decrease the tolerance of the spinal cord to radiation. This report describes a case of radiation myelitis in a patient after concomitant fluorouracil/cisplatin chemotherapy and extended field radiotherapy for stage IIA adenosquamous cell carcinoma of the uterine cervix metastatic to the para-aortic lymph nodes. © 1991.

引用

页码：305 / 308

页数：4

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