REGIOSELECTIVE SN' ALLYLIC SUBSTITUTION VERSUS 1,4-ADDITION - ASYMMETRIC INDUCTION WITH OPPOLZER CHIRAL SULTAM

被引：7

作者：

GIRARD, C ^{[1
]}

MANDVILLE, G ^{[1
]}

BLOCH, R ^{[1
]}

机构：

[1] UNIV PARIS 11,INST CHIM MOLEC ORSAY,CNRS,CARBOCYCLES LAB,BAT 420,F-91405 ORSAY,FRANCE

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 04期

关键词：

D O I：

10.1016/S0957-4166(00)80161-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The reaction of organocuprate reagents R'2Cu(CN)Li2.BF3 with gamma-bromo conjugated N-acyl sultams derived from camphor gave, with high regio- and stereoselectivity, compounds arising from a SN' allylic substitution. Reductive removal of the chiral auxiliary furnished alpha-substituted beta, gamma-unsaturated alcohols of excellent enantiomeric purity.

引用

页码：613 / 616

页数：4

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