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PROGRESS IN MASS-SPECTROMETRY OF NUCLEIC-ACID CONSTITUENTS - ANALYSIS OF XENOBIOTIC MODIFICATIONS AND MEASUREMENTS AT HIGH MASS

被引：43
作者：
MCCLOSKEY, JA
CRAIN, PF
机构：
[1] Department of Medicinal Chemistry, University of Utah, Salt Lake City
来源：
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY | 1992年 / 118卷
关键词：
D O I：
10.1016/0168-1176(92)85077-D
中图分类号：
O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号：
070203 ; 070304 ; 081704 ; 1406 ;
摘要：
Significant recent progress in the applications of mass spectrometry in nucleic acid chemistry has been realized in two diverse areas. These are the characterization and quantification of xenobiotically modified nucleic acid constituents, and the mass spectrometry of large oligonucleotides, primarily by electrospray and laser desorption methods. Selected examples of the literature in these two fields are reviewed for the period 1988 through mid-1991.
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页码：593 / 615
页数：23
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