THE CROONIAN LECTURE, 1993 - THE ENDOTHELIUM - MAESTRO OF THE BLOOD-CIRCULATION

被引:82
作者
VANE, JR
机构
关键词
D O I
10.1098/rstb.1994.0023
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The vascular endothelium plays a vital role in the control of the circulation. It metabolizes various vasoactive substances, coverts angiotensin I to angiotensin II and secretes the potent vasodilators prostacyclin and EDRF(NO) and the vasoconstrictor peptide endothelin-1. The balance between these mediators determines the responses of the cardiovascular system in diseases such as hypertension, atherosclerosis and myocardial infarction.
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页码:225 / 246
页数:22
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