MITOTIC-ACTIVITY OF THE ENDOCRINE-CELLS IN RAT-THYROID GLANDS DURING POSTNATAL LIFE

被引:18
作者
CONDE, E
MARTINLACAVE, I
UTRILLA, JC
MORENO, A
GONZALEZCAMPORA, R
GALERADAVIDSON, H
机构
[1] UNIV SEVILLE, FAC MED, DEPT NORMAL & PATHOL CYTOL & HISTOL, AVDA DR FEDRIANI S-N, E-41009 SEVILLE, SPAIN
[2] UNIV SEVILLE, FAC MED, DEPT CELLULAR BIOL, SEVILLE, SPAIN
关键词
D O I
10.1210/en.131.1.436
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This paper presents the results of investigations into the mitotic rates of thyroid endocrine cells in normal postnatal rats, aged 1-120 days. Our study revealed considerable age-dependent shifts in the mean mitotic activity of follicular cells and C-cells. The maximum indices of endocrine cell renewal were reached during the first 10 days of life, decreasing gradually and significantly until 25 days. At 1 month, there was a significant recuperation of the division rate for both cell types, which declined in the adult rat. These results mean that the proliferation of C-cells and follicular cells is inversely proportional to age. The preferential zone of localization of mitoses of both cell types is the central region of the thyroid lobe. The present paper provides new evidence for the postnatal origin of C-cells and follicular cells from the preexisting endocrine cells.
引用
收藏
页码:436 / 440
页数:5
相关论文
共 37 条
[1]  
BAKER DE, 1979, LABORATORY RAT, V1, P154
[2]   HISTOMETRY OF NORMAL THYROID IN MAN [J].
BROWN, RA ;
ALMOUSSA, M ;
BECK, JS .
JOURNAL OF CLINICAL PATHOLOGY, 1986, 39 (05) :475-482
[3]   STRUCTURE OF RAT ULTIMOBRANCHIAL BODIES AFTER BIRTH [J].
CALVERT, R .
ANATOMICAL RECORD, 1975, 181 (03) :561-579
[4]   TRANSITIONAL CELLS IN POSTNATAL THYROID-GLAND OF RAT [J].
CALVERT, R .
ANATOMICAL RECORD, 1972, 174 (03) :341-&
[5]  
CHAN AS, 1971, LAB INVEST, V25, P249
[6]   HISTOMETRY OF NORMAL THYROID-GLANDS IN NEONATAL AND ADULT-RATS [J].
CONDE, E ;
MARTINLACAVE, I ;
GONZALEZCAMPORA, R ;
GALERADAVIDSON, H .
AMERICAN JOURNAL OF ANATOMY, 1991, 191 (04) :384-390
[7]  
CONDE E, IN PRESS ANAT HISTOL
[8]   Complex IV in the dog with special emphasis on the relation of the ultimobranchial body to interfollicular cells in the postnatal thyroid gland [J].
Godwin, MC .
AMERICAN JOURNAL OF ANATOMY, 1937, 60 (02) :299-339
[9]  
HARACH HR, 1987, ACTA ANAT, V129, P27
[10]  
HARACH HR, 1985, CELL TISSUE RES, V242, P211