ENGINEERING PROTEIN ORIENTATION AT SURFACES TO CONTROL MACROMOLECULAR RECOGNITION EVENTS

被引：32

作者：

MCLEAN, MA ^{[1
]}

STAYTON, PS ^{[1
]}

SLIGAR, SG ^{[1
]}

机构：

[1] BECKMAN INST ADV SCI & TECHNOL, 405 N MATHEWS ST, URBANA, IL 61801 USA

来源：

ANALYTICAL CHEMISTRY | 1993年 / 65卷 / 19期

关键词：

D O I：

10.1021/ac00067a021

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this report we demonstrate that heterologous protein-protein interactions can be controlled at an immobilization surface by genetically engineering an appropriately de novo designed attachment point on the protein surface.

引用

页码：2676 / 2678

页数：3

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