PREPARATION OF N-ARYLATED HETEROCYCLES BY NUCLEOPHILIC AROMATIC-SUBSTITUTION

被引：48

作者：

STABLER, SR

JAHANGIR

机构：

[1] Institute of Organic Chemistry, Syntex Discovery Research, Palo Alto

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 01期

关键词：

D O I：

10.1080/00397919408012635

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nucleophilic aromatic substitution of fluorobenzoates and fluorophenylnitriles with weakly basic heterocycles readily occur. This synthetic methodology is utillized to produce potent angiotensin-II antagonists.

引用

页码：123 / 129

页数：7

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