HEPATIC CYTOCHROME LEVEL IN THE CAT (FELIS-CATUS) - NORMAL VALUE AND VARIATIONS IN RELATION TO SOME BIOLOGICAL PARAMETERS

被引:5
作者
MAUGRAS, M [1 ]
REICHART, E [1 ]
机构
[1] INSERM,UNITE PHYSIOPATHOL RESP U14,F-54500 VANDOEUVRE,FRANCE
来源
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1979年 / 64卷 / 01期
关键词
D O I
10.1016/0305-0491(79)90196-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. 1. The average level of the hepatic hydroxylating cytochrome was determined in the cat (0.380 ± 0.085 nmol · mg-1 proteins). 2. 2. Great individual differences were noted. 3. 3. The level of cytochrome increases with age in the immature (age ≤8.5 months) and young adults (age: 10-18 months). It is diminished in the older animals. 4. 4. The measured average level is lower than that in other species, and approaches the human one. 5. 5. The induction capacity of phenobarbital is lower in the cat than in other mammals, for example the rat or the mouse. © 1979.
引用
收藏
页码:125 / 127
页数:3
相关论文
共 7 条
[1]  
Altman PL., 1976, CELL BIOL
[2]   PREPARATION AND COMPARED ANALYSIS OF CAT LIVER MICROSOMAL FRACTIONS [J].
AZZAR, G ;
ROUGIER, M ;
BERTHILLIER, G ;
GOT, R .
BIOCHIMIE, 1976, 58 (03) :285-295
[3]   METABOLIC INTERACTIONS AMONG ENVIRONMENTAL CHEMICALS AND DRUGS [J].
CONNEY, AH ;
BURNS, JJ .
SCIENCE, 1972, 178 (4061) :576-+
[4]  
GILLETTE JR, 1969, MICROSOMES DRUGS OXI
[5]  
LOWRY OH, 1951, J BIOL CHEM, V193, P265
[6]  
OMURA T, 1964, J BIOL CHEM, V239, P2370
[7]  
TAKESHITA M, 1966, BIOLOGICAL CHEMICAL, P145