CLONING AND SEQUENCING OF A CDNA-ENCODING THE CANINE HSP27 PROTEIN

被引：13

作者：

LARSEN, JK

GERTHOFFER, WT

HICKEY, E

WEBER, LA

机构：

[1] UNIV NEVADA, DEPT BIOL 314, RENO, NV 89557 USA

[2] UNIV NEVADA, SCH MED, DEPT PHARMACOL, RENO, NV 89557 USA

来源：

GENE | 1995年 / 161卷 / 02期

关键词：

HEAT-SHOCK PROTEIN; COLONIC CDNA LIBRARY; SMOOTH MUSCLE;

D O I：

10.1016/0378-1119(95)00290-M

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The nucleotide (nt) sequence encoding a 27-kDa heat-shock protein (HSP27) was determined from cDNAs cloned from a canine smooth muscle library. The primary structure deduced from the nt sequence reveals a 209-amino-acid protein having 86-89% identity with human, mouse, rat and hamster small HSP. Similar to human HSP27, the canine protein contains three Ser residues that are potential MAPKAP kinase II substrates.

引用

页码：305 / 306

页数：2

共 12 条

[1] HSP27 IS A MEDIATOR OF SUSTAINED SMOOTH-MUSCLE CONTRACTION IN RESPONSE TO BOMBESIN [J].