CHANGES IN COAGULATION-FACTORS IN POST-MENOPAUSAL WOMEN ON ETHINYL ESTRADIOL

被引：12

作者：

HUNTER, DJS

ANDERSON, ABM

HADDON, M

机构：

[1] UNIV OXFORD,JOHN RADCLIFFE HOSP,NUFFIELD DEPT OBSTET & GYNAECOL,OXFORD OX3 9DU,ENGLAND

[2] CHURCHILL HOSP,OXFORD HAEMOPHILIA CTR,PLASMA FRACTIONAT LAB,OXFORD OX3 7LJ,ENGLAND

来源：

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1979年 / 86卷 / 06期

关键词：

D O I：

10.1111/j.1471-0528.1979.tb10795.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Coagulation factors II, VII, X, VII X complex and anti‐thrombin III were measured in 10 postmenopausal women before, during and after a four‐month course of 20 μg daily of ethinyl oestradiol, taken three weeks in four. Factors VII, X and VII X complex rose significantly during treatment but only factor X levels were significantly elevated at the end of the four‐month treatment period. There was no change in factor II or anti‐thrombin III levels. These effects on coagulation factors during ethinyl oestradiol therapy are, in general, similar to those found during treatment with conjugated equine oestrogens and oestradiol valerate in a previous study from the same laboratory. It seems likely that equipotent doses of ethinyl oestradiol and‘natural’oestrogens have similar effects on these coagulation factors. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：488 / 490

页数：3