URINARY LEVELS OF INTERLEUKIN-6 AND DISEASE-ACTIVITY IN PATIENTS WITH IGA NEPHROPATHY

被引：38

作者：

TOMINO, Y ^{[1
]}

FUNABIKI, K ^{[1
]}

OHMURO, H ^{[1
]}

SHIMIZU, M ^{[1
]}

YOKOYAMA, K ^{[1
]}

SHIRATO, I ^{[1
]}

SHIRAI, T ^{[1
]}

TAKAHASHI, M ^{[1
]}

KOIDE, H ^{[1
]}

机构：

[1] JUNTENDO UNIV, SCH MED, DEPT PATHOL, TOKYO 113, JAPAN

来源：

AMERICAN JOURNAL OF NEPHROLOGY | 1991年 / 11卷 / 06期

关键词：

INTERLEUKIN-6; RENAL HISTOLOGY; IGA NEPHROPATHY;

D O I：

10.1159/000168359

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We studied, using ELISA, 27 patients with IgA nephropathy to determine if levels of urinary interleukin-6 (IL-6) might reflect the disease activity. The levels of urinary IL-6 in patients with the advanced stage were significantly higher than those in patients with the mild stage of the disease or in healthy adults. The results showed a significant correlation between the levels of urinary IL-6 and the disease activity, i.e., levels of urinary cast and urinary protein. It was thus suggested that the measurement of urinary IL-6 is useful in evaluating the degree of glomerular injuries and/or prognosis in patients with IgA nephropathy.

引用

页码：459 / 464

页数：6

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