A NEW APPROACH TO THE BICYCLIC HYDROXYLAMINE HEMIKETAL RING-SYSTEM OF ANTITUMOR-ANTIBIOTIC FR900482 VIA OXIDATIVE RING EXPANSION OF A TETRAHYDROPYRROLO[1,2-A]INDOLE

被引：29

作者：

DMITRIENKO, GI

DENHART, D

MITHANI, S

PRASAD, GKB

TAYLOR, NJ

机构：

[1] Guelph-Waterloo Centre for Graduate work in Chemistry, University of Waterloo, Waterloo, Ont. N2L 3G1, Waterloo Campus

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 39期

关键词：

D O I：

10.1016/0040-4039(92)89011-Z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The bicyclic hydroxylamine hemiketal ring system found in antitumour antibiotic FR900482 can be produced via an oxidative ring expansion of the 9a-hydroxy-2,3,9,9a-tetrahydro-1H-pyrrolo[1,2-a]indole ring system by reaction with Davis' reagent.

引用

页码：5705 / 5708

页数：4

共 22 条

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