THE CHEMISTRY OF ENOXYSILACYCLOBUTANES - HIGHLY SELECTIVE, UNCATALYZED ALDOL ADDITIONS

被引：50

作者：

DENMARK, SE

GRIEDEL, BD

COE, DM

机构：

[1] Roger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 05期

关键词：

D O I：

10.1021/jo00057a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

O-(Silacyclobutyl)ketene acetals derived from esters, thiol esters, and amides reacted with a variety of aldehydes at room temperature without the need for catalysts. The O,O-ketene acetal of E-configuration reacted rapidly to afford the syn aldol products with high diastereoselectivity (93/7-99/1).

引用

页码：988 / 990

页数：3

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