MEIGE SYNDROME IN THE SPECTRUM OF LEWY BODY DISEASE

被引：36

作者：

MARK, MH

SAGE, JI

DICKSON, DW

HEIKKILA, RE

MANZINO, L

SCHWARZ, KO

DUVOISIN, RC

机构：

[1] UNIV MED & DENT NEW JERSEY,ROBERT WOOD JOHNSON MED SCH,DEPT PATHOL NEUROPATHOL,NEW BRUNSWICK,NJ 08903

[2] ALBERT EINSTEIN COLL MED,DEPT PATHOL NEUROPATHOL,BRONX,NY 10467

[3] ALBERT EINSTEIN COLL MED,DEPT NEUROL,BRONX,NY 10467

来源：

NEUROLOGY | 1994年 / 44卷 / 08期

关键词：

D O I：

10.1212/WNL.44.8.1432

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report a patient with Meige syndrome (segmental cranial dystonia) who had neuropathologic changes of Parkinson's disease on postmortem examination. Neuropathologic examination showed typical and atypical Lewy bodies in the pigmented nuclei of the brainstem (substantia nigra, locus ceruleus), the nucleus basalis of Meynert, and the nucleus ambiguus. Neurochemical analysis of postmortem brain tissue showed evidence for decreased dopamine turnover in the substantia nigra, striatum, and nucleus accumbens. We propose that some cases of Meige syndrome may be included in the spectrum of Lewy body disease.

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页码：1432 / 1436

页数：5

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