AFRAMODIAL AND OTHER BIOACTIVE DITERPENOIDS FROM AFRAMOMUM SPECIES

被引：23

作者：

AYAFOR, JF

TCHUENDEM, MHK

NYASSE, B

TILLEQUIN, F

ANKE, H

机构：

[1] UNIV KAISERSLAUTERN, DEPT BIOTECHNOL, W-6750 KAISERSLAUTERN, GERMANY

[2] UNIV PARIS 05, FAC PHARM, CNRS, URA 3010, F-75270 PARIS 06, FRANCE

来源：

PURE AND APPLIED CHEMISTRY | 1994年 / 66卷 / 10-11期

关键词：

D O I：

10.1351/pac199466102327

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The biological activity of the potential therapeutic agent, 8beta, 17-epoxy-12E-labdene-15,16-dial (aframodial) 1, has been briefly reviewed. Ten other Cameroonian Aframomum species have been investigated as potentially improved sources for 1 and their aframodial content analyzed. In the course of these investigations three novel diterpenoids, aulacocarpinolide, aulacocarpin A, and aulacocarpin B, were isolated from A. aulacocarpos and their structures determined as 2, 3. and 4, respectively. In the structural elucidation, particular use was made of high-field 1D 2D and 3D NMR spectroscopic techniques.

引用

页码：2327 / 2330

页数：4

共 7 条

[1] STRUCTURE OF A LABDANE DIALDEHYDE FROM AFROMOMUM-DANIELLII (ZINGIBERACEAE) [J].