PLASMA DIGOXIN CONCENTRATION IN DIFFERENT AGE-GROUPS

被引：4

作者：

LANG, D ^{[1
]}

HOFSTETTER, R ^{[1
]}

VONBERNUTH, G ^{[1
]}

机构：

[1] UNIV ULM,ZENTRUM INNERE MED & KINDERHEILKUNDE,DEPT KINDERHEILKUNDE,D-7900 ULM,FED REP GER

来源：

KLINISCHE WOCHENSCHRIFT | 1978年 / 56卷 / 02期

关键词：

Age-dependent pharmacokinetics of digoxin; Plasma digoxin concentration;

D O I：

10.1007/BF01480089

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma digoxin concentration during maintenance therapy with digoxin was determined in premature and mature newborns, infants, children and adults. The plasma digoxin concentration of newborns was significantly higher than in adults; in addition, in the group of premature newborns it also was higher than in infants and children. These differences in plasma digoxin concentrations may be explained by differences in dose, volume of distribution and excretion rate of digoxin in the various age groups. © 1978 Springer-Verlag.

引用

页码：93 / 95

页数：3

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