CA2+-MOBILIZING RECEPTORS OF GASTRULATING CHICK-EMBRYO

被引：31

作者：

LAASBERG, T

机构：

[1] Laboratory of Molecular Genetics, Institute of Chemical Physics and Biophysics, 200026 Tallinn, Estonia

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY | 1990年 / 97卷 / 01期

关键词：

D O I：

10.1016/0742-8413(90)90164-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Gastrulating chick embryo cells (stages 3-5 by HH) possess Ca2+-mobilizing receptors for ACh and ATP; insulin and noradrenaline have a weaker effect on [Ca2+]i mobilization. 2. The ED50 value for ACh is 4 (+/-0.5). 10(-6) M and for ATP 20 (+/-5). 10(-6) M. 3. Addition of ACh and ATP to dissociated chick embryo cells causes rapid accumulation of IP3. 4. The stimulatory effects of ACh and ATP on [Ca2+]i mobilization and IP3 rapid formation are both additive.

引用

页码：9 / 12

页数：4

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