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THE INS AND OUTS OF THE TRANSMEMBRANE-4 SUPERFAMILY

被引：334
作者：
WRIGHT, MD
TOMLINSON, MG
机构：
[1] Institute of Medical Research, PO Royal Melbourne Hospital, Melbourne, 3050 Vic., The Walter and Eliza Hall
[2] The MRC Cellular Immunology Unit, Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, South Parks Road
来源：
IMMUNOLOGY TODAY | 1994年 / 15卷 / 12期
关键词：
D O I：
10.1016/0167-5699(94)90222-4
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The recently discovered transmembrane 4 superfamily comprises a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains, which are presumed to be membrane spanning. At least seven of these molecules are expressed on leukocytes, and it seems likely that they mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
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页码：588 / 594
页数：7
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