CEREBROSPINAL-FLUID AND PERIPHERAL WHITE BLOOD-CELL RESPONSE TO ACUTE CEREBRAL-ISCHEMIA

被引：16

作者：

SUZUKI, S ^{[1
]}

KELLEY, RE ^{[1
]}

REYESIGLESIAS, Y ^{[1
]}

ALFONSO, VM ^{[1
]}

DIETRICH, WD ^{[1
]}

机构：

[1] UNIV MIAMI, SCH MED, DEPT NEUROL, MIAMI, FL USA

来源：

SOUTHERN MEDICAL JOURNAL | 1995年 / 88卷 / 08期

关键词：

D O I：

10.1097/00007611-199508000-00005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We prospectively evaluated the inflammatory response to acute cerebral ischemia in 57 patients who were seen within 72 hours of ictus. All subjects had cerebrospinal fluid examination, complete blood count, sedimentation rate determination, and body temperature monitoring. Correlation analysis was done between these measurements and infarct volume, which was determined by computed tomography of the brain. We found a positive linear correlation between infarct size and the peripheral white blood cell count, specifically the polymorphonuclear leukocyte count. A relationship was also observed for the cerebrospinal fluid protein level, the gamma globulin level, and the cerebrospinal fluid/serum albumin ratio. The correlations observed presumably reflect the extent of tissue injury and secondary inflammatory response in acute cerebral ischemia.

引用

页码：819 / 824

页数：6

共 40 条

[1]

ADAMS RD, 1968, INTRO NEUROPATHOLOGY, P172

[2]

Altman, 1991, PRACTICAL STAT MED R, P277

[3]

BAGBY GC, 1992, CECILS TXB MED, P914

[4] SMALL DIFFERENCES IN INTRAISCHEMIC BRAIN TEMPERATURE CRITICALLY DETERMINE THE EXTENT OF ISCHEMIC NEURONAL INJURY [J].