STRUCTURE OF THE GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR GENE IN PATIENTS WITH THE MYELODYSPLASTIC SYNDROMES

被引:5
作者
BOULTWOOD, J
ABRAHAMSON, G
BUCKLE, VJ
RACK, K
OSCIER, DG
WAINSCOAT, JS
机构
[1] JOHN RADCLIFFE HOSP,LEUKAEMIA RES FUND,MOLEC & CYTOGENET HAEMATOL UNIT,OXFORD OX3 9DU,ENGLAND
[2] ROYAL VICTORIA HOSP,DEPT HAEMATOL,BOURNEMOUTH,DORSET,ENGLAND
关键词
colony‐stimulating factor; gene rearrangement;
D O I
10.1002/ajh.2830340215
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
DNA samples from 76 patients with the myelodysplastic syndromes, including 10 cases with a partial deletion of the long arm of chromosome 5 (5q‐), were examined for structural rearrangements of the granulocyte/macrophage colony‐stimulating factor (GM‐CSF) gene. No abnormalities were detected, indicating that structural aberrations of this gene are not a feature of the myelodysplastic syndromes. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company
引用
收藏
页码:157 / 158
页数:2
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