Women and Lung Cancer: What is New?

被引：80

作者：

North, Crystal M. ^{[1
]}

Christiani, David C. ^{[1
,2
]}

机构：

[1] Massachusetts Gen Hosp, Dept Med, Pulm & Crit Care Unit, Boston, MA 02114 USA

[2] Harvard Sch Publ Hlth, Dept Environm Hlth, Environm Genet, 665 Huntington Ave,1-1401, Boston, MA 02115 USA

来源：

SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY | 2013年 / 25卷 / 02期

关键词：

lung cancer; women; risk factors; genetic mutations;

D O I：

10.1053/j.semtcvs.2013.05.002

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

In the last 20 years, there has been an increased focus on gender differences in health and disease. The earliest studies of lung cancer enrolled mainly men, as the incidence of lung cancer among women was exceedingly low. As social patterns changed around World War II and women began to smoke more, the epidemiology of lung cancer has changed. The higher percentage of lung cancer in nonsmoking women as compared with nonsmoking men suggests that lung cancer behaves differently in women. Studies of lung cancer in women indicate that there are differences in risk factors, histology, pathophysiology, treatment outcomes, and prognosis as compared with men. The purpose of this review is to provide a concise summary of the literature on lung cancer as it pertains to women, with an emphasis on new areas of research and treatment options. © 2013 Elsevier Inc.

引用

页码：87 / 94

页数：8

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